Are we closer to selective immunotherapy for autoimmune diseases?

Are we closer to selective immunotherapy for autoimmune diseases?

Source :

• Immunology Today [ 0167-5699 ] ; 1994.

English descriptors

• Teeft :
  • 3etermining binding, Aberrant recognmon, Abnormal circumstances, Additional contact, Akbough peptides, Alan lamont, Allele, Allelic gene products, Allelic polymorphism, Allelic proteins, Amino acids, Anchor bind, Anchor residues, Animal models, Antigen antibody administration, Antigen presentation, Antithe issue, Applicable mice, Autoimmune, Autoimmune disease, Autoimmune diseases, Autoimmune response, Basis therapy, Bind autoantigens, Bind peptide, Binding site alleles, Cambridgeh addressine, Cause thymocyte apoptosis, Cell surface, Cellular level, Central binding core, Cessory molecules, Chaperone calnexin, Chaperone proteins, Chemical properties, Chimeric antibody, Class antigen, Class peptides, Clinical benefit, Clinical signs, Closer examination, Complete anergy, Complex field, Comprehensive analysis, Conjunction role, Constant generation, Crude mixtures, Crvmic determinants, Cryptic determinants, Deeper states, Defiae binding motifs, Detectable insulitis, Diabetogenic plexes, Different class, Different immunodominam epitopes, Different responses, Different sets, Discussion viewpoint, Disdate autoantigen, Disease activity, Disease onset comwere upregulated, Efficient phenomena, Endogenous clone, Endoplasmic reticulum, Endosomal compartments, Endosomal fnncrinnal aspects, Exogenous peptide competitor, Experimental immunology today, Expression syndromes, First instance, Fruitful area, Functional pockets, Functionel implications, Further details, Further development, Further selection, Gain access, Garden city, Gene expression, Good binders, High proportior, High resolution, Higher affinity, Human disease, Human papilloma virus, Hydrophobic anchor residues, Immtmodeficiency diseases, Immunological research, Immunology today, Implications treatment, Important antigen, Important implications ditional, Infectious agents, Interesting model, Iris opening remarks, Islet self sented, Large phase, Larger phase, Local tissue destruction, Lymph nodes, Major histocompatibility, Many aspects, Mhcblocking peptides, Mice show, Model system, Multiple states, Mune system, Negative selection, Next symposium, Nondepleting sessions, Novel immunotherapies, Other acthat, Other antigens, Peer review, Pepamino acids, Peptde libraries disprocesn, Peptide, Peptide affinity, Peptide antigen, Peptide assnciarion witk, Peptide binding, Peptide library, Peptide motifs binding, Peptidebased therapy, Peptides mice, Peripheral deletion, Peripheral models, Peripheral tolerance, Pockets orientated, Polymorpbic groove, Polymorphic residues, Pool sequencing, Preformed antibodies, Preliminary data, Promiscuous structure, Protective alleles, Reasonable association constants, Recent data, Recent results, Reeerse diabetes, Reinduction apoptosis, Relative increases, Relative instability, Responses intramolecu, Rheumatoid arthritis, Roche milano ricerche, Roche research centre, Same cell, Second sercarz angeles, Secondary mtchor residues, Selective immunotherapy, Self antigens, Several immunotherapeutic strategies, Shallower pockets, Shallower rammensee, Short course, Significant reduction, Similar degrcc, Similar levels, Similar physico, Similar principles, Similar studies, Size constraints, Specific positions, Specific processing, Split ified, Stable fashion, Strominger iboston, Subsequent response, Symposium ident, Symposium title, Tandem mass spectroscopy, Tcell activation, Tcrantagonist peptides, Therapy bach, Tide residues, Tile antibody, Time points, Tolerant cells, Transactivator ciita, Transporter genes, Tumour necrosis factor, Ultimate goal, Ultrastrnctural information, Unresponsiveness intermolecularly, Usceptibility alleles, Viewpoint articles, Viewpoint manuscripts, Viewpoint sectioi, Vital role, Whole spectrum.

Abstract

• https://api.istex.fr/ark:/67375/6H6-C0S477DD-F/fulltext.pdf

Affiliations:

• Royaume-Uni

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